Korelasi Kadar Bilirubin Total Dengan Estimasi Laju Filtrasi Glomerolus Pada Penderita Penyakit Ginjal Kronik

Authors

  • Nuraddiyani Hidayah
  • Ria Triwardhani

DOI:

https://doi.org/10.36408/mhjcm.v5i1.343

Abstract

Latar belakang: Penyakit Ginjal Kronik (PGK) merupakan gangguan fungsi renal yang progresif dan ireversibel. Estimasi laju filtrasi glomerolus (eLFG) merupakan indeks untuk menilai fungsi ginjal. Stress oksidatif sebagai salah satu penyebab terjadinya disfungsi renal pada PGK. Bilirubin merupakan antioksidan dan mempunyai kemampuan renoprotektif. Tujuan penelitian untuk menganalisis korelasi kadar bilirubin total serum dengan eLFG pada penderita PGK. 

Metode: Penelitian belah lintang berdasarkan rekam medik penderita PGK di RSUP Dr. Kariadi pada Agustus 2015 – Juli 2016. Analisis statistik untuk korelasi kadar bilirubin total serum dengan eLFG menggunakan uji korelasi Spearman.

Hasil: Lima puluh dua penderita PGK dengan median (min-maks) kadar bilirubin total serum 0,55(0,22-2,10) mg/dl dan eLFG 11,75(3,4-112,60) ml/menit/1,73m2. Uji korelasi Spearman kadar bilirubin total serum dengan eLFG didapatkan r = 0,419; p = 0,002.  

Simpulan: Terdapat korelasi positif sedang yang bermakna antara kadar bilirubin total serum dengan eLFG. Bilirubin mempunyai kemampuan renoprotektif sehingga dengan mengetahui kadar bilirubin total serum dapat membantu mengetahui derajat progresifitas PGK.

 

Kata kunci : penyakit ginjal kronik, bilirubin total serum, eLFG

 

Downloads

Download data is not yet available.

Additional Files

Published

2018-05-09

How to Cite

1.
Hidayah N, Triwardhani R. Korelasi Kadar Bilirubin Total Dengan Estimasi Laju Filtrasi Glomerolus Pada Penderita Penyakit Ginjal Kronik. Medica Hospitalia J. Clin. Med. [Internet]. 2018 May 9 [cited 2024 Apr. 19];5(1). Available from: http://medicahospitalia.rskariadi.co.id/medicahospitalia/index.php/mh/article/view/343

Issue

Vol. 5 No. 1 (2018): Med Hosp; Mei 2018

Section

Original Article

Citation Check

License

Copyrights Notice
Copyrights:
Researchers publishing manuscrips at Medica Hospitalis: Journal of Clinical Medicine agree with regulations as follow:
Copyrights of each article belong to researchers, and it is likewise the patent rights
Researchers admit that Medica Hospitalia: Journal of Clinical Medicine has the right of first publication
Researchers may submit manuscripts separately, manage non exclusive distribution of published manuscripts into other versions (such as: being sent to researchers’ institutional repository, publication in the books, etc), admitting that manuscripts have been firstly published at Medica Hospitalia: Journal of Clinical Medicine
License:
Medica Hospitalia: Journal of Clinical Medicine is disseminated based on provisions of Creative Common Attribution-Share Alike 4.0 Internasional It allows individuals to duplicate and disseminate manuscripts in any formats, to alter, compose and make derivatives of manuscripts for any purpose. You are not allowed to use manuscripts for commercial purposes. You should properly acknowledge, reference links, and state that alterations have been made. You can do so in proper ways, but it does not hint that the licensors support you or your usage.