Hubungan Hemoglobin Terglikosilasi (HbA1c) Dengan Risiko Kardiovaskular Pada Pasien Diabetes Mellitus

Authors

  • Hadian Widyatmojo Bagian Patologi Klinik Fakultas Kedokteran Universitas Diponegoro, Semarang, Indonesia
  • Lisyani Budipradigda Suromo Bagian Patologi Klinik Fakultas Kedokteran Universitas Diponegoro/ RSUP Dr. Kariadi, Indonesia

DOI:

https://doi.org/10.36408/mhjcm.v7i2.500

Keywords:

DM, HbA1c, Skor risiko Interheart

Abstract

Latar belakang : Diabetes Mellitus (DM) dengan kondisi hiperglikemik kronik  dapat mengakibatkan gangguan sistem kardiovaskular dan peningkatan  mortalitas. Hemoglobin terglikosilasi (HbA1c) merupakan salah satu parameter untuk pengendalian DM. Tujuan penelitian untuk membuktikan adanya hubungan antara kadar HbA1c serum dengan risiko kardiovaskular pada pasien DM.

Metode : Penelitian belah lintang dilakukan pada 42 penderita DM yang dirawat di RSUP Dr. Kariadi Semarang periode Agustus - September 2017. Diagnosis DM didapatkan melalui rekam medis. Dilakukan pemeriksaan HbA1c dan dinilai faktor risiko yang terdapat pada rekam medis menggunakan skor interheart (IHR). Analisa statistik menggunakan uji korelasi Spearman.

Hasil : Terdapat hubungan antara HbA1c dengan skor IHR dengan nilai r=0,887, p=0,001. Pasien dengan kategori risiko kardiovaskular tinggi memiliki nilai HbA1c dengan rerata 10,12 ± 2,29, skor kategori sedang 6,62 ± 1,67 dan skor kategori rendah 5,75 ± 0,78.

Simpulan :Terdapat hubungan positif kuat antara HbA1c dengan risiko kardiovaskular pada pasien DM. Perlu dilakukan penelitian prospektif dengan sampel yang lebih besar.

Kata kunci

DM, HbA1c, Skor risiko Interheart

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References

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Additional Files

Published

2020-11-19

How to Cite

1.
Widyatmojo H, Suromo LB. Hubungan Hemoglobin Terglikosilasi (HbA1c) Dengan Risiko Kardiovaskular Pada Pasien Diabetes Mellitus. Medica Hospitalia J. Clin. Med. [Internet]. 2020 Nov. 19 [cited 2024 Dec. 22];7(2):379-83. Available from: http://medicahospitalia.rskariadi.co.id/medicahospitalia/index.php/mh/article/view/500

Issue

Vol. 7 No. 2 (2020): Med Hosp; Nov 2020

Section

Original Article

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