Risk Factors of Diabetic Retinopathy with Type 2 Diabetes Mellitus

Authors

  • Nisa Khoirun Nafia Diponegoro University, Indonesia
  • Trilaksana Nugroho
  • Arief Wildan
  • Hari Peni Julianti
  • Hery Djagat Purnomo

DOI:

https://doi.org/10.36408/mhjcm.v8i3.596

Keywords:

diabetic retinopathy, risk factor, type 2 diabetes mellitus

Abstract

BACKGROUND: More than 75% of people with type 2 DM will anguish diabetic retinopathy 20 years after being diagnosed. However, the current changing of people’s lifestyle contributes to the tendency in type 2 DM that diagnosed at a younger age. This causes diabetic retinopathy can be occurred earlier and blindness will occur more quickly. It is important to prevent diabetic retinopathy by controlling some associated factors.

OBJECTIVE: To investigate associated factors of diabetic retinopathy in people with type 2 DM.

METHOD: Analytic observational study with cross-sectional design. Subjects were determined by purposive sampling. The subjects were interviewed using a questionnaire meanwhile, funduscopic examination is aimed to assess diabetic retinopathy and followed by deep interview. This study also used the subject’s medical record to complete the required data. The results were analyzed by using statistic software.

RESULT: From 43 subjects, there wes no significant relation among age (p=0.965), gender (p=0.437), level of knowledge (p=0.640), accessibility (p=1.000), economic level (p=0.680), duration of DM (p=0.477), history of hypertension (p=0.708), and history of dyslipidemia (p=0.244) with diabetic retinopathy in people with type 2 DM. However, there was significant relation among controlling blood glucose (p=0.014) with diabetic retinopathy in people with type 2 DM. Uncontrolled blood glucose was 13 times more affected in diabetic retinopathy than controlled blood glucose (OR 13.417, 95% CI:1.474-122.117).

CONCLUSION: There was a significant relation between controlling blood glucose and diabetic retinopathy in people with type 2 DM. Controlling blood glucose is the most dominant risk factor among the other factors in this study.

Keywords: diabetic retinopathy; risk factor; type 2 diabetes mellitus

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References

1. World Health Organization. Global Report on Diabetes. Isbn. 2016;978:88.
2. Prof.dr.Suharjo, SU. SM, Dr.Hartono S. Buku Ilmu Kesehatan Mata. 1st ed. Bagian Ilmua Penyakit Mata FK UGM; 2013. 116–119 p.
3. Kementerian Kesehatan RI. Retinopati Diabetik: Pergeseran Paradigma Kebutaan pada Era Milenial. 2018.
4. Sharma A, Sharma A. Retina and Vitreous. Mindmaps Ophthalmol. 2019;245–84.
5. Yunia A dkk. Perbandingan Risiko Terjadinya Retinopati Diabetik Antara Pasien Hipertensi Dan Non Hipertensi yang Mengidap Diabetes Melitus di RSUD Majenang. MEDISAINS J Ilm Ilmu-ilmu Kesehat. 2017;15(1):31–8.
6. Li N et al. Diabetes Self-Management and Its Association With Diabetic Retinopathy in Patients With Type 2 Diabetes. Chinese J Ophthalmol. 2013;49(6):500–6.
7. Rajalakshmi R, Amutha A, Ranjani H, Ali MK, Unnikrishnan R, Mohan R, et al. Journal of Diabetes and Its Complications Prevalence and risk factors for diabetic retinopathy in Asian Indians with young onset Type 1 and Type 2 Diabetes. J Diabetes Complications. 2014;28(3):291–7.
8. Dewi PN, Fadrian, Vitresia H. Profil Tingkat Keparahan Retinopati Diabetik dengan Atau Tanpa Hipertensi di RSUP Dr. M. Djamil Padang. J Kesehat Andalas. 2019;8(2):204–10.
9. Ahsan H. Diabetic retinopathy - Biomolecules and multiple pathophysiology. Diabetes Metab Syndr Clin Res Rev. 2015;9(1):51–4.
10. Chisha Y, Terefe W, Assefa H, Lakew S. Prevalence and factors associated with diabetic retinopathy among diabetic patients at Arbaminch General Hospital , Ethiopia?: Cross sectional study. 2017;1–9.
11. Anugrah J. Hubungan Diabetes Melitus dan Retinopati di RSUD dr Soedarso Pontianak Periode Januari-Desember 2010. J Mhs FK UNTAN. 2013;2(1):1–12.
12. Utami DR, Amin R, Zen F. Karakteristik Klinis Pasien Retinopati Diabetik Periode 1 Januari 2014 – 31 Desember 2015 di RSUP Dr . Mohammad Hoesin Palembang. Maj Kedokt Sriwij. 2017;49(2):66–74.
13. Sumarto SM. Faktor Faktor yang Berhubungan dengan Kejadian Retinopati Diabetik pada Penderita Diabetes Melitus Tipe 2 di Poli Penyakit Dalam RSPAD Gatot Soebroto. Repos UPN Veteran Jakarta. 2017;
14. CH NIB. Faktor-Faktor yang Mempengaruhi Retinopati Diabetik. Repos Univ Airlangga. 2015;
15. Mahbubah IP. Hubungan Faktor Risiko (Usia, Jenis Kelamin, Lama Menderita Diabetes Melitus, Kadar Glukosa Darah) dengan Derajat Retinopati Diabetik Setelah Follow Up 5 Tahun. Repos Univ Muhammadiyah Malang. 2014;
16. Balasopoulou A, ?okkinos P, Pagoulatos D, Plotas P, Makri OE, Georgakopoulos CD, et al. Diabetic retinopathy and risk factors for sight threatening diabetic retinopathy in people with type 2 diabetes in India. BMC Ophthalmol. 2020;68(1):521–6.
17. Shi L, Singh DB. Delivering Health Care in America. sixth edit. Jones and Bartlett Learning; 2015. 49–53 p.
18. Prof Dr Soekidjo Notoatmodjo. Ilmu Perilaku Kesehatan. Rineka Cipta; 2014.
19. World Health Organization. A Global Brief on Hypertension. In World Health Organization, Switzerland; 2013.
20. Donnelly R, Horton E. Pathophysiology of Diabetic. Vasc Complicat Diabetes. 2012;9:1–6.
21. Salinero-Fort MÁ, San Andrés-Rebollo FJ, de Burgos-Lunar C, Arrieta-Blanco FJ, Gómez-Campelo P. Four-Year Incidence of Diabetic Retinopathy in a Spanish Cohort: The MADIABETES Study. PLoS One. 2013;8(10).

Additional Files

Published

2021-11-05

How to Cite

1.
Nafia NK, Nugroho T, Wildan A, Julianti HP, Purnomo HD. Risk Factors of Diabetic Retinopathy with Type 2 Diabetes Mellitus. Medica Hospitalia J. Clin. Med. [Internet]. 2021 Nov. 5 [cited 2024 Dec. 21];8(3):265-72. Available from: http://medicahospitalia.rskariadi.co.id/medicahospitalia/index.php/mh/article/view/596

Issue

Vol. 8 No. 3 (2021): Med Hosp; Nov 2021

Section

Original Article

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