Relationship between Hypertension and Classification of Lumbar Herniated Nucleus Pulposus Based on Magnetic Resonance Imaging
DOI:
https://doi.org/10.36408/mhjcm.v8i3.598Keywords:
Disc Degeneration, Lumbar Herniated Nucleus Pulposus, HypertensionAbstract
ABSTRACT
BACKGROUND : Hypertension is a disease that is known to affect other diseases. Recent research finds that HT is associated with disc degeneration disease. Herniated nucleus pulposus (HNP) lumbar as a result from disc degeneration disease need to be known to be affected by hypertension or not.
OBJECTIVE: To know the relationship between hypertension and the classification of disc degeneration based on Pfirrmann’s criteria and herniated nucleus pulposus lumbar classification based on magnetic resonance imaging.
METHOD : This research use descriptive observational with cross sectional design. Subjects were 62 lumbar HNP patients diagnosed at RSUP Dr. Kariadi Semarang from January 2019 - March 2020. The subject data were analyzed using non-parametric Chi Square test and Mantel Haenszel test.
RESULT : Based on the analysis, it was found that p>0.05 was found in the relationship between age and sex with the classification of disc degeneration and lumbar HNP. The result of correlation test between hypertension and disc degeneration classification is p<0,05 with odds ratio 14,700 and lumbar HNP classification is p >0.05. In relation to the classification of disc degeneration with lumbar HNP classification, the value of p >0.05 was also obtained.
CONCLUSION : There was no association between age, sex, the classification of disc degeneration and lumbar HNP classification. There was a significant association between hypertension and the classification of disc degeneration with the individual risk of hypertension increasing 14,7 times but no association was found with lumbar HNP classification.
Keywords: Disc degeneration; Hypertension; Lumbar herniated nucleus pulposus
Downloads
References
2. De Cicco F, Willhuber G. Nucleus Pulposus Herniaton. In: StatPearls. Treasure Island (FL) : StatPearls Publishing. 2020. Retrieved (https://www.ncbi.nlm.nih.gov/books/NBK542307/)
3. Unger T BC, Charchar F, Khan NA, Poulter NR, Prabhakaran D, Ramirez A, et al. 2020 International Society of Hypertension Global Hypertension Practice Guidelines. American Heart Association. 2020 ;75:1334-1357. Retrieved (https://doi.org/10.1161/HYPERTENSIONAHA.120.15026)
4. Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Oka H, et al. Metabolic Syndrome Components Are Associated with Intervertebral Disc Degeneration: The Wakayama Spine Study. PLoS One. 2016;11:e0147565-e0147565. Retrieved (https://dx.doi.org/10.1371%2Fjournal.pone.0147565)
5. Kauppila LI. Atherosclerosis and Disc Degeneration/Low-Back Pain-A Systematic Review. Elsevier. 2009;37:661-670. Retrieved (https://doi.org/10.1016/j.ejvs.2009.02.006)
6. Samartzis D, Bow C, Karppinen J, Luk KDK, Cheung BMY, Cheung KMC. Hypertension is Independently Associated with Lumbar Disc Degeneration: A Large-Scale Population-Based Study. Global Spine Journal. 2014. Retrieved (https://doi.org/10.1055%2Fs-0034-1376579)
7. Donnally III C, Hanna A, Varacallo M. Lumbar Degenerative Disc Disease. In: StatPearls. Treasure Island (FL); Statpearls Publishing. 2019. Retrieved (https://www.ncbi.nlm.nih.gov/books/NBK448134/)
8. Bednar DA. Cauda equina syndrome from lumbar disc herniation. Canadian Medical Association journal. 2016;188:284-284. Retrieved (https://dx.doi.org/10.1503%2Fcmaj.150206)
9. Baptista JdS, Fontes RBdV, Liberti EA. Aging and degeneration of the intervertebral disc: review of basic science. Coluna/Columna. 2015;14:144-148. Retrieved (https://doi.org/10.1590/S1808-185120151402141963)
10. Barani R KAA. Multi-Level Disc Degeneration in Young Individuals - A Prospective MRI Study of 100 Computer Professionals. EC Orthopaedics. 2018;9. Retrieved (https://www.ecronicon.com/ecor/pdf/ECOR-09-00260.pdf)
11. Siemionow K, An H, Masuda K, Andersson G, Cs-Szabo G. The effects of age, sex, ethnicity, and spinal level on the rate of intervertebral disc degeneration: a review of 1712 intervertebral discs. Spine (Phila Pa 1976). 2011;36(17):1333-1339. Retrieved (https://dx.doi.org/10.1097%2FBRS.0b013e3181f2a177)
12. Wang YXJ, Griffith JF, Zeng XJ, Deng M, Kwok AWL, Leung JCS, et al. Prevalence and sex difference of lumbar disc space narrowing in elderly chinese men and women: osteoporotic fractures in men (Hong Kong) and osteoporotic fractures in women (Hong Kong) studies. Arthritis Rheum. 2013;65:1004-1010. Retrieved (https://doi.org/10.1002/art.37857)
13. Fajar JK AA. Surgical of Lumbar Disc Herniation in Aceh, Indonesia: Description in 28 Patients. Journal of Health Sciences. 2017;7:132-136. Retrieved (https://doi.org/10.17532/jhsci.2017.433)
14. Rizzolo SJ, Piazza MR, Cotler JM, Balderston RA, Schaefer D, Flanders A. Intervertebral Disc Injury Complicating Cervical Spine Trauma. Spine . 1991;16:S187-S189. Retrieved (https://doi.org/10.1097/00007632-199106001-00002)
15. Burke JG, Watson RW, McCormack D, Dowling FE, Walsh MG, Fitzpatrick JM. Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators. The Journal of bone and joint surgery British volume. 2002;84:196-201. Retrieved (https://doi.org/10.1302/0301-620x.84b2.12511)
16. Safti? R, Grgi? M, Ebling B, Splavski B. Case-control study of risk factors for lumbar intervertebral disc herniation in Croatian island populations. Croat Med J. 2006;47:593-600. Retrieved (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080445/)
17. Seidler A, Bolm-Audorff U, Siol T, Henkel M, Fuchs C, Schug H, et al. Occupational risk factors for symptomatic lumbar disc herniation; a case-control study. Occupational and Environmental Medicine. 2003;60:821. Retrieved (https://dx.doi.org/10.1136%2Foem.60.11.821)
18. Sheng B, Feng C, Zhang D, Spitler H, Shi L. Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis. Int J Environ Res Public Health. 2017;14:183. Retrieved (https://dx.doi.org/10.3390%2Fijerph14020183)
19. Saleem S, Aslam HM, Rehmani MA, Raees A, Alvi AA, Ashraf J. Lumbar disc degenerative disease: disc degeneration symptoms and magnetic resonance image findings. Asian Spine J. 2013;7(4):322-334. Retrieved (https://dx.doi.org/10.4184%2Fasj.2013.7.4.322)
Additional Files
Published
How to Cite
Issue
Section
Citation Check
License
Copyright (c) 2021 Medica Hospitalia : Journal of Clinical Medicine
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Copyrights Notice
Copyrights:
Researchers publishing manuscrips at Medica Hospitalis: Journal of Clinical Medicine agree with regulations as follow:
Copyrights of each article belong to researchers, and it is likewise the patent rights
Researchers admit that Medica Hospitalia: Journal of Clinical Medicine has the right of first publication
Researchers may submit manuscripts separately, manage non exclusive distribution of published manuscripts into other versions (such as: being sent to researchers’ institutional repository, publication in the books, etc), admitting that manuscripts have been firstly published at Medica Hospitalia: Journal of Clinical Medicine
License:
Medica Hospitalia: Journal of Clinical Medicine is disseminated based on provisions of Creative Common Attribution-Share Alike 4.0 Internasional It allows individuals to duplicate and disseminate manuscripts in any formats, to alter, compose and make derivatives of manuscripts for any purpose. You are not allowed to use manuscripts for commercial purposes. You should properly acknowledge, reference links, and state that alterations have been made. You can do so in proper ways, but it does not hint that the licensors support you or your usage.