The Correlation Between Tympanogram with Location and Size of The Tumor in Nasopharyngeal Carcinoma Patients

Authors

  • Julita Melisa Dewi Program Studi Ilmu Kesehatan THT-KL, Fakultas Kedokteran, Universitas Diponegoro Semarang, Indonesia
  • Dwi Marliyawati Program Studi Ilmu Kesehatan THT-KL, Fakultas Kedokteran, Universitas Diponegoro Semarang, Indonesia
  • Muyassaroh Muyassaraoh KSM Ilmu Kesehatan THT-KL RSUP Dr. Kariadi/ Fakultas Kedokteran, Universitas Diponegoro Semarang, Indonesia

DOI:

https://doi.org/10.36408/mhjcm.v9i1.682

Keywords:

Nasopharyngeal carcinoma, tympanometry, eustachian tube, hearing loss

Abstract

Introduction : Hearing loss is the most frequent symptomps of patients with Nasopharyngeal Carcinoma (NPC), because there is a connection between the middle ear and the nasopharynx through the eustachian tube. Tympanometry is a hearing test in terms of evaluating the middle ear.

Objective : This study aimed to evaluate the correlation between the tympanogram and the location and size of the nasopharyngeal carcinoma tumor at Dr. Kariadi General Hospital Semarang.

Methods : This is a descriptive analytic study with cross-sectional study design of  NPC patients at Dr. Kariadi Hospital Semarang, July 2020 to June 2021. Tympanometry was performed at the beginning of the diagnosis of NPC, the location and size of the tumor based on a head and neck physical examination, nasopharyngoscopy and CT scan results. Data analysis with spearmen rho . test.

Result : From 52 subjects were diagnosed with NPC, most of them were in the 5th decade. The most common location of the tumor was in Rossenmuler fossa and extended to the wall and roof of the nasopharynx bilaterally (n=29; 55,7%). The most tumor size was T4 (n=26;50%). The results of statistical analysis showed that the tympanogram image had a strong correlation with the location of the tumor in NPC patients (r=0.853; p<0.001), but had no correlation with tumor size (r=0.061; p=0.668).

Conclusion : The tympanogram in NPC is related to the location of the tumor, not to the size of the tumor.

 

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References

Chen YP, Chan ATC, Le QT, Blanchard P, Sun Y, Ma J. Nasopharyngeal carcinoma. Vol. 394, The Lancet. Lancet Publishing Group; 2019. p. 64–80.

Adham M, Hermani B, Kurniawan AN, Muhtadi AI, Roezin A, Gondhowiardjo S, et al. Karsinoma nasofaring di Indonesia: epidemiologi, insiden, tanda, dan gejala pada presentasi. Jurnal kanker Cina. 2012;31(4):185.

Muyassaroh, Tri lestari. Pengaruh Perawatan Paliatif terhadapPeningkatan Kualitas Hidup Penderita Karsinoma NasofaringStadium Lanjut di RSUP Dr. Kariadi Semarang. Med Hosp. 2019;6(2):125–30.

Utama DS. Audiometry Finding in Nasopharyngeal Carcinoma Patients in ENT-HN Department of Mohammad Hoesin General Hospital Palembang 1 June 2016-1 June 2020. IJNPC . 2021;03(02):42–4.

Cahyadi I, Dewi YA. Status Pendengaran pada Penderita Karsinoma Nasofaring. Tt. 2014;1.

Tobing DI. Karsinoma Nasofaring Tahap Awal: Laporan Kasus. Jurnal Internasional Karsinoma Nasofaring. 2019;1(02):75–7.

Hidayat B. Hubungan antara gambar timpanometri dengan letak dan stadium tumor pada penderita karsinoma nasofaring di departemen tht-kl rsup h. adam malik medan. [Medan: Gudang]; 2009.

Schilder AGM, Chonmaitree T, Cripps AW, Rosenfeld RM, Casselbrant ML, Haggard MP, et al. Otitis media. Nature Reviews Disease Primers. 2016 Sep 8;2.

Aquinas R. Talakasana Otitis Media Efusi pada Anak. . Cermin Dunia Kedokteran. 2017;44(7):472–7.

Anugrahani A, Bogi Soeseno, Dewi YA, Aroean NA. The Comparison Of Elevated Levels Of Ebv Immunoglobulin A Early Antigen Between Nasopharyngeal Carcinoma Who Type 3 With Malignant Non-Hodgkin Lymphoma. International Journal Of Nasopharyngeal Carcinoma (IJNPC). 2019 Sep 17;1(02):41–4.

Xiao G, Cao Y, Qiu X, Wang W, Wang Y. Influence of gender and age on the survival of patients with nasopharyngeal carcinoma. BMC Cancer. 2013 Dec 4;13(1):226.

Li W-Z, Lv S-H, Liu G-Y, Liang H, Xia W-X, Xiang Y-Q. Age-dependent changes of gender engaruh Perawatan Paliatif terhadapPeningkatan Kualitas Hidup Penderita Karsinoma NasofaringStadium Lanjut di RSUP Dr. Kariadi Semarang. Med Hosp. 2019;6(2):125–30. NPC . 2021;03(02):42–4.

Kein W, Low C, Rangabashyam M. Masalah Terkait Telinga pada Pasien dengan Karsinoma Nasofaring. Dalam: Karsinogenesis, Diagnosis, dan Target Molekuler untuk Karsinoma Nasofaring. . Singapura Dalam Teknologi. 2012;155–78.

Mulyanto J, Darmawan AB, Kapti A. Socioeconomic inequality in stage at diagnosis of nasopharyngeal carcinoma: a cross-sectional study. Oto Rhino Laryngologica Indonesiana. 2016 Jul 12;46(1):44.

Carle LN, Ko CC, Castle JT. Nasopharyngeal Carcinoma. Head and Neck Pathology. 2012 Sep 10;6(3):364–8.

Tsunoda A, Suzuki M, Kishimoto S, Anzai T, Matsumoto F, Ikeda K, et al. Otitis Media With Effusion Caused by a Parapharyngeal Tumor Showing Normal Nasopharyngeal Findings. Ear, Nose & Throat Journal. 2021 Aug 13;100(7):543–5.

Additional Files

Published

2022-03-28

How to Cite

1.
Dewi JM, Marliyawati D, Muyassaraoh M. The Correlation Between Tympanogram with Location and Size of The Tumor in Nasopharyngeal Carcinoma Patients. Medica Hospitalia J. Clin. Med. [Internet]. 2022 Mar. 28 [cited 2024 Dec. 22];9(1):43-7. Available from: http://medicahospitalia.rskariadi.co.id/medicahospitalia/index.php/mh/article/view/682

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