Prevalensi, Onset, dan Durasi Gangguan Olfaktori dan Gangguan Gustatori pada Kasus COVID 19
Prevalence, Onset, and Duration of Olfactory and Gustatory dysfunction on COVID 19 case
DOI:
https://doi.org/10.36408/mhjcm.v9i2.688Keywords:
COVID 19, gangguan olfactori, gangguan gustatoriAbstract
LATAR BELAKANG : Kasus gangguan olfaktori dan gustatori meningkat pada pandemi COVID 19, hal ini dihubungkan dengan sel epitel pernapasan dan sel epitel penyokong olfaktori mengekspresikan banyak protein ACE2 yang merupakan reseptor virus SARS-Cov2 untuk menginfeksi sel. Pasca infeksi virus memang sudah dikenal sebagai salah satu penyebab anosmia/hiposmia. Penelitian lanjut masih dibutuhkan untuk menambah bukti sebagai bahan pertimbangan mempelajari prevalensi, pola gangguan olfaktori dan gustatori, penyembuhan, tatalaksana dan prognosisnya
TUJUAN : Mengetahui prevalensi, onset dan durasi gangguan olfaktori dan gustatori pada subyek yang terkonfirmasi positif COVID 19 dengan pemeriksaan swab PCR.
METODE : Penelitian observasional dengan metode belah lintang pada pasien terkonfirmasi positif COVID-19 dengan pemeriksaan swab PCR di RSUP Dr.Kariadi Semarang yang memenuhi kriteria inklusi. Sampel diminta pengisian data lewat googleform
HASIL : Prevalensi gangguan olfaktori dan gustatori pada pada subyek yang terkonfirmasi positif COVID 19 dengan pemeriksaan swab PCR yaitu 61% (115 orang), onset gejala terjadi sebelum terkonfirmasi COVID 19 yaitu pada 75% (86 orang) dan 71% (82 orang) sembuh kurang dari 2 minggu, terbanyak pada 5-8 hari yaitu 32% (37 orang).
KESIMPULAN : Prevalensi gangguan olfaktori dan gustatori cukup tinggi sehingga temuan gejala ini merupakan gejala penting untuk deteksi dini kasus COVID 19.
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