Correlation Between Body Mass Index, Gender, and Age With Cholelithiasis

Correlation Between Body Mass Index, Gender, and Age With Cholelithiasis

Authors

  • Fatimah Al Atsariyah Faculty of Medicine, Diponegoro University Semarang, Indonesia, Indonesia
  • Bernardus Parish Budiono Department of Digestive Surgery, Faculty of Medicine, Diponegoro University Semarang, Indonesia, Indonesia
  • Endang Mahati Department of Pharmacology, Faculty of Medicine, Diponegoro University Semarang, Indonesia, Indonesia
  • Dwi Lestari Partiningrum Department of Internal Medicine, Faculty of Medicine, Diponegoro University Semarang, Indonesia, Indonesia

DOI:

https://doi.org/10.36408/mhjcm.v9i3.771

Keywords:

Body Mass Index (BMI), Gender, Age, Cholelithiasis.

Abstract

BACKGROUND : Gallstones are formed due to deposit or hypersaturation of one or more of the bile components, namely cholesterol, bilirubin, bile salts, calcium, protein, fatty acids, and phospholipids. BMI, gender, and age are the factors that can trigger the formation of gallstones. In Indonesia, cholelithiasis cases have received less attention because they are often asymptomatic, making it difficult to detect and often misdiagnosed, resulting in a lack of official publication about the incidence of gallstones in Indonesia.

AIM : To determine the correlation between BMI, Gender, and Age with cholelitiasis in Dr. Kariadi Hospital.

METHOD : This was an observational study using cross-sectional design. Data were taken from medical records of patients in Digestive Surgery Department Dr. Kariadi Hospital from January 2018 until March 2020. A total of 100 patients were selected as subjects (50 patients with cholethiasis and 50 patienst without cholelithiasis). Pearson Chi-Square correlation was used for statistical analysis.

RESULTS : Pearson Chi-Square test of BMI (p = 0.001) and Age (p = 0.041) was statistically significant for cholelithiasis risk (p < 0.05). While Gender (p = 0.224) was not statistically significant for cholelithiasis risk.

CONCLUSION : There wa a significant correlation between BMI and Age with Cholelithiasis and there was no significant correlation between Gender with Cholelithiasis.

KEYWORDS : Body Mass Index (BMI), Gender, Age, Cholelithiasis.

Downloads

Download data is not yet available.

References

Lesmana LA. Hepatobilier : Penyakit Batu Empedu. In: Aru W. Sudoyo, BambanG Setiyohadi, Idrus Alwi, Marcellus, Simadibrata SS, editor. Buku Ajar Ilmu Penyakit Dalam Jilid II. 6th ed. Jakarta: Interna Publishing; 2015. p. 2027–2022.

Price SA, Wilson LMC, Anugrah P, Dharma A, Wijaya C. Kolelitiasis. In: Widjaja C, editor. Patofisiologi Konsep Proses-Proses Penyakit. 6th ed. Jakarta: Penerbit Buku Kedokteran EGC; 2015. p. 530–515.

Stinton LM, Shaffer EA. Epidemiology of gallbladder disease: Cholelithiasis and cancer. Gut Liver. 2016;6(2):172–87. Available form : https://pubmed.ncbi.nlm.nih.gov/22570746/

Chang YR, Jang J-Y, Kwon W, Park JW, Kang MJ, Ryu JK, et al. Changes in Demographic Features of Gallstone Disease: 30 Years of Surgically Treated Patients. Gut Liver. 2016;7(6):719–24. Available from : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848536/

Pak M, Lindseth G. Risk factors for cholelithiasis. Gastroenterol Nurs. 2016;39(4):297–309. Available from : https://pubmed.ncbi.nlm.nih.gov/27467059/

Purwanti A, Maliya A, Zulaicha E. Hubungan Gaya Hidup Dengan Kejadian Penyakit Cholelitiasis Di Ruang Rawat Inap Rsi Surakarta [Internet]. Publikasi Ilmiah Universitas Muhammadiyah Surakarta. 2016 [cited 2020 Feb 15]. Available from: http://eprints.ums.ac.id/id/eprint/43021

Depkes RI. Sistem Kesehatan Nasional [Internet]. 2015 [cited 2020 Feb 26]. Available from: http://www.depkes.go.id

Liu T, Wang W, Ji Y, Wang Y, Liu X, Cao L, et al. Association between different combination of measures for obesity and new-onset gallstone disease. PLoS One. 2018;13(5):1–11. Available from : https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196457

Nurhikmah R, Efriza, Abdullah D. Hubungan Peningkatan Indeks Massa Tubuh dengan Kejadian Kolelitiasis di Bagian Bedah Digestif RSI Siti Rahmah Padang Periode Januari-Juni 2018. Heal Med J. 2018;I(2):1–6. Available from : https://jurnal.unbrah.ac.id › article › download

Kiani Q, Farooqui F, Khan MS, Khan AZ, Nauman Tariq M, Akhtar A. Association of Body Mass Index and Diet with Symptomatic Gall Stone Disease: A Case-Control Study. Cureus. 2020;12(3):1–8. Available from : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135725/

Lavoie JM. Dynamics of hepatic and intestinal cholesterol and bile acid pathways: The impact of the animal model of estrogen deficiency and exercise training. World J Hepatol. 2016;8(23):961–975. Available from : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990760/

Kharga B, Sharma BK, Singh VK, Nishant K, Bhutia P, Tamang R, et al. Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMI. J Clin Diagnostic Res. 2016;10(10):PC28–32. Available from : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121732/

Ansari-Moghaddam A, Khorram A, Miri-Bonjar M, Mohammadi M, Ansari H. The Prevalence and Risk Factors of Gallstone Among Adults in South-East of Iran: A Population-Based Study. Glob J Health Sci. 2016;8(4):60–7. Available from : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873599/

Sueta MAD, Warsinggih. Risk Factors of Gallstones At Dr . Wahidin Sudirohusodo General Hospital Makassar. J Bedah Nas. 2017;1(1):20–6. DOI :10.24843/JBN.2017.V01.I01.P04

Hu J, Chen M, Yeh C, Chiu W, Chiang M, Chang M. Effects of gender and age on prevalence of cholelithiasis in patients with chronic HCV infection. Med Balt. 2018;97(22):e10846. Available from : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392741/

Figueiredo JC, Haiman C, Porcel J, Buxbaum J, Stram D, Tambe N, et al. Sex and ethnic/racial-specific risk factors for gallbladder disease. BMC Gastroenterol. 2017;17:153. Available from : https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-017-0678-6

Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P. Age of menopause and impact of climacteric symptoms by geographical region. Climacteric. 2016;13(5):419–28. Available from : https://pubmed.ncbi.nlm.nih.gov/20690868/

Rosenthal MS. The Gynecological Sourcebook: When They Tell You It’s Cancer. USA: McGraw-Hill; 2017. 272–279 p.

Sevinç H, Demir MS, Mercan C, Yüksel F, Çaylan A. The Age And Gender Presentation In The Formations Of Gallstones. Turkish Med Student J. 2017;4:11–3. Available from : https://dergipark.org.tr/tr/download/article-file/404693

Douglas M Heuman. Epidemiology of Gallstones (Cholelithiasis) [Internet]. Medscape. 2020 [cited 2020 Feb 25]. Available from: https://emedicine.medscape.com/article/175667-overview#a5

Wibiwo S, Kanandihardja W, Sjamsuhidayat R, Syukur A. Saluran Empedu dan Hati. In: Wibiwo S, Kanandihardja W, Sjamsuhidayat R, Syukur A, editors. Buku Ajar Ilmu Bedah. 3rd ed. Jakarta: Penerbit Buku Kedokteran EGC; 2012. p. 767–73.

Additional Files

Published

2022-11-30

How to Cite

1.
Al Atsariyah F, Parish Budiono B, Mahati E, Lestari Partiningrum D. Correlation Between Body Mass Index, Gender, and Age With Cholelithiasis : Correlation Between Body Mass Index, Gender, and Age With Cholelithiasis . Medica Hospitalia J. Clin. Med. [Internet]. 2022 Nov. 30 [cited 2024 Apr. 25];9(3):280-5. Available from: http://medicahospitalia.rskariadi.co.id/medicahospitalia/index.php/mh/article/view/771

Issue

Section

Original Article

Citation Check