Correlation Procalcitonin (PCT) to Neutrophil Lymphocyte Ratio (NLR) in Covid-19 Patient

Authors

  • Isnawati Apriliani Department of Medical Laboratory Technology, Health Polytechnique of Jakarta III Jakarta Indonesia, Indonesia
  • Rizana Fajrunni’mah Department of Medical Laboratory Technology, Health Polytechnique of Jakarta III Jakarta Indonesia, Indonesia
  • Husjain Djajaningrat Department of Medical Laboratory Technology, Health Polytechnique of Jakarta III Jakarta Indonesia, Indonesia
  • Aninda Dinar Widiantari Research Installation, Sulianti Saroso Infectious Disease Hospital Jakarta, Indonesia, Indonesia
  • Farida Murtiani Research Installation, Sulianti Saroso Infectious Disease Hospital Jakarta, Indonesia, Indonesia https://orcid.org/0000-0003-4992-117X

DOI:

https://doi.org/10.36408/mhjcm.v10i1.855

Keywords:

COVID-19, Procalcitonin (PCT), Neutrophil Lymphocyte Ratio (NLR)

Abstract

BACKGROUND: Covid-19 treatment should be done early before the disease progress. Inflammatory biomarker is needed to ascertain the severity of disease as soon as possible.  Neutrophil-to-lymphocyte ratio (NLR) and Procalcitonin (PCT) are two of biomarker that are clinically used around the world. NLR is simpler, can routinely be done and available in peripheral region while PCT is more effective to describe inflammation.

PURPOSE: This study aims to determine the correlation of procalcitonin (PCT) levels with neutrophil lymphocyte ratio (NLR) in COVID-19 patients.

METHOD: This study is an analytic observational with a cross sectional design. We extracted data from medical record. Samples were 415 COVID-19 patients undergoing inpatient care at the Budhi Asih Hospital, East Jakarta for January - December 2021.

RESULTS: Prevalence of male patients more than ≥60 years were 78 patients (18,8%) while female patients were 68 patients (16,4%). Average of PCT level was 1,93 ng/mL (0,02-200 ng/mL). Average of NLR was 5,09 cells/mm3 (0,22-31 cells/mm3). Spearman test proved there was a significant correlation between PCT and NLR levels in COVID-19 patients (p value = 0,0001).

CONCLUSION: The higher the PCT level, the higher the NLR value in COVID-19 patients.

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References

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Additional Files

Published

2023-03-31

How to Cite

1.
Apriliani I, Fajrunni’mah R, Djajaningrat H, Widiantari AD, Murtiani F. Correlation Procalcitonin (PCT) to Neutrophil Lymphocyte Ratio (NLR) in Covid-19 Patient. Medica Hospitalia J. Clin. Med. [Internet]. 2023 Mar. 31 [cited 2024 May 3];10(1):98-101. Available from: http://medicahospitalia.rskariadi.co.id/medicahospitalia/index.php/mh/article/view/855

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