Pemberian Vitamin C sebagai Antioksidan terhadap Fragilitas Osmotik Eritrosit pada Thalassemia Mayor

Authors

  • Ricki Rajagukguk
  • Sholeh Kosim
  • Moedrik Tamam

DOI:

https://doi.org/10.36408/mhjcm.v2i2.100

Abstract

Latar belakang : Vitamin C berperan sebagai antioksidan untuk
melawan peroksidasi membran fosfolipid yang disebabkan oleh
stres oksidatif sehingga diharapkan dapat memperbaiki fragilitas
osmotic mendekati rentang normal. Pemeriksaan fragilitas
osmotik eritrosit dulu sejarahnya dilakukan untuk uji tapis beta
thalassemia mayor. Tranfusi darah masih merupakan pengobatan
utama untuk menanggulangi anemia pada thalassemia pada saat
ini. Pemberian tranfusi berulang menyebabkan penimbunan besi
yang berlebihan yang selanjutnya mengakibatkan kerusakan
oksidatif. Tujuan penelitian ini untuk membuktikan apakah
pemberian vitamin C dapat memperbaiki fragilitas osmotik
eritrosit pada pasien β thalassemia

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Published

2014-10-02

How to Cite

1.
Rajagukguk R, Kosim S, Tamam M. Pemberian Vitamin C sebagai Antioksidan terhadap Fragilitas Osmotik Eritrosit pada Thalassemia Mayor. Medica Hospitalia J. Clin. Med. [Internet]. 2014 Oct. 2 [cited 2024 Apr. 27];2(2). Available from: http://medicahospitalia.rskariadi.co.id/medicahospitalia/index.php/mh/article/view/100

Issue

Vol. 2 No. 2 (2014): Med Hosp; Mei 2014

Section

Original Article

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